Orbelli

Complete Ingredient Profile

Ingredient Name & Common Synonyms

Primary Name: Zinc (as Zinc Bisglycinate)
Common Synonyms: Zinc chelate, Zinc glycinate, Elemental zinc
Chemical Classification: Essential trace mineral, Chelated mineral
Molecular Formula: C₄H₈N₂O₄Zn

Overview

Botanical Family: Naturally occurring in Brassicaceae (seeds), Fabaceae (legumes), Poaceae (grains)
Primary Origin: Oysters, beef, pumpkin seeds, chickpeas, cashews, quinoa
Extraction Method: Chelation process binding zinc to glycine amino acids for enhanced absorption
Molecular Structure: Zinc ion bound to two glycine molecules forming stable chelate complex
Appearance: Light tan to beige powder, nearly odorless with mild metallic taste

Benefits & Uses

For Women's Hormonal Health:

Hormone Synthesis: Zinc is essential for the production and regulation of key hormones including testosterone, estrogen, and progesterone
PCOS Support: Zinc supplementation helps improve insulin sensitivity and reduces inflammation associated with PCOS
Reproductive Health: Critical for ovarian function, egg quality, and maintaining healthy menstrual cycles

Primary Health Benefits:

Immune Function: Essential for development and function of immune cells (T-cells, NK cells) and immune system response
Antioxidant Support: Component of superoxide dismutase, protecting cells from oxidative damage and free radicals
Wound Healing: Critical for collagen synthesis, tissue repair processes, and cellular regeneration
Growth & Development: Required for normal growth, development, cellular reproduction, and protein synthesis

Mechanism of Action:

Enzyme Cofactor: Essential component of metalloenzymes throughout the body for catalytic functions
Gene Expression: Regulates transcription factors and gene expression for immune and metabolic pathways
Cell Signaling: Functions as a signaling molecule in immune and metabolic pathways
Membrane Stability: Maintains cellular membrane integrity and supports cellular transport processes

Safety & Warnings

General Safety Profile:

Zinc bisglycinate is well-tolerated with superior absorption compared to other zinc forms. Our 5mg dose provides optimal support without risk of toxicity.

Dosage Safety:

Standard Dosage: 8-11mg daily recommended intake for adults
Orbelli Dosage: 5mg per serving provides 45% of the daily value
Maximum Safe Dose: Up to 40mg daily is considered the upper limit for long-term use

Potential Side Effects:

Digestive Effects: High doses may cause nausea, vomiting, or stomach upset
Copper Interference: Excessive zinc can interfere with copper absorption
Throat Irritation: May cause mild throat irritation in some individuals - this is normal and typically resolves quickly

Important Warnings:

Mineral Balance: Avoid exceeding the recommended dose to prevent mineral imbalances
Drug Interactions: May reduce the absorption of certain antibiotics and medications
Empty Stomach: Taking on an empty stomach may increase nausea risk
Consult a healthcare provider if taking medications or having digestive conditions

Recommended Patch-Test Instructions:

Not applicable for oral supplements. For topical applications containing zinc, perform a 48-hour patch test on the inner forearm.

Formulation Tips

Physical Properties:

pH Range: 6.0-7.0 (neutral in aqueous solution)
Solubility: Highly soluble in water due to the chelated form
Stability: Stable across a wide pH range, heat-stable up to 200°C
Absorption: Superior bioavailability compared to zinc oxide or sulfate

Optimal Dosing:

Therapeutic Range: 5-15mg daily for general health support
Orbelli Formula: 5mg per serving (optimal absorption dose)
Bioavailability: Enhanced absorption due to glycinate chelation
Timing: Can be taken with or without food, better tolerance with meals

Pairing Suggestions:

Synergistic with: Vitamin C, vitamin A, selenium
Compatible with: Most vitamins and minerals in appropriate ratios
Avoid with: High-dose iron or calcium (may compete for absorption)
Enhanced by: Amino acids and organic acids for absorption

Scientific References

The Nutritional Roles of Zinc for Immune System - Frontiers in Nutrition, 2024
Zinc as a Gatekeeper of Immune Function - PMC, 2017
Zinc Supplementation and Immune Factors: Systematic Review - PubMed, 2021
Zinc and Immune Function: The Biological Basis - PubMed, 1998

Related Orbelli Products

Women's Hormonal Balance - Features 5mg Zinc for immune function and hormone synthesis support
Synergistically combined with selenium and other mineral cofactors
Additional product links to be added

Last updated: August 2025 | This information is for educational purposes only and not intended as medical advice.