Orbelli

Complete Ingredient Profile

Ingredient Name & Common Synonyms

Primary Name: Vitamin B6 (Pyridoxine HCl)
Common Synonyms: Pyridoxine, Pyridoxal, Pyridoxamine, Pyridoxine Hydrochloride
Chemical Classification: Water-soluble vitamin, B-complex vitamin
Molecular Formula: C₈H₁₁NO₂

Overview

Botanical Family: Naturally occurring in Poaceae (grains), Fabaceae (legumes), Solanaceae (potatoes)
Primary Origin: Chickpeas, tuna, salmon, chicken breast, potatoes, bananas, fortified cereals
Extraction Method: Industrial synthesis or extraction from natural sources, followed by crystallization and purification
Molecular Structure: Pyridine derivative with hydroxymethyl and amino groups
Appearance: White to off-white crystalline powder, odorless with a slightly bitter taste

Benefits & Uses

For Women's Hormonal Health:

Neurotransmitter Balance: B6 is essential for producing serotonin and dopamine, which directly influence mood regulation and hormonal cycles
PMS Support: Vitamin B6 helps reduce PMS symptoms by supporting neurotransmitter production and hormonal balance
Estrogen Metabolism: B6 plays a crucial role in estrogen metabolism, helping the body process and eliminate excess hormones

Primary Health Benefits:

Protein Metabolism: Essential cofactor for over 100 enzyme reactions involving amino acid metabolism and protein synthesis
Neurotransmitter Production: Required for the synthesis of serotonin, dopamine, and GABA for optimal mood and cognitive function
Immune Function: Supports healthy immune system response, antibody production, and white blood cell activity
Energy Production: Facilitates conversion of stored glycogen to glucose and supports cellular energy metabolism

Mechanism of Action:

Enzyme Cofactor: Acts as a cofactor for aminotransferases and decarboxylases in protein metabolism
Gene Expression: Influences gene expression related to immune and metabolic functions
Neurotransmitter Synthesis: Direct role in converting precursor amino acids to neurotransmitters
Cellular Function: Essential for DNA synthesis, red blood cell formation, and nervous system function

Safety & Warnings

General Safety Profile:

Vitamin B6 is generally safe when taken at recommended doses. Our 10mg dose is well within safe therapeutic ranges established by clinical research.

Dosage Safety:

Standard Dosage: 1.3-2.0mg daily recommended intake for adults
Orbelli Dosage: 10mg per serving provides therapeutic levels for optimal benefits
Maximum Safe Dose: Up to 100mg daily is considered safe for long-term use

Potential Side Effects:

High Dose Effects: Doses above 200mg daily may cause peripheral neuropathy
Digestive Effects: Rare mild nausea or stomach upset in sensitive individuals
Throat Irritation: May cause mild throat irritation in some individuals - this is normal and typically resolves quickly

Important Warnings:

Pregnancy/Breastfeeding: Safe at recommended doses, consult healthcare provider
Medication Interactions: May interact with certain seizure medications
Neuropathy Risk: Avoid exceeding 100mg daily without medical supervision
Consult a healthcare provider if taking medications for Parkinson's disease

Recommended Patch-Test Instructions:

Not applicable for oral supplements. For topical applications containing B6, perform a 48-hour patch test on the inner forearm.

Formulation Tips

Physical Properties:

pH Range: 2.4-3.0 (acidic in aqueous solution)
Solubility: Freely soluble in water (22g/100mL), slightly soluble in alcohol
Stability: Light-sensitive, stable in acidic conditions, degrades in alkaline solutions
Melting Point: 204-206°C

Optimal Dosing:

Therapeutic Range: 10-50mg daily for metabolic support
Orbelli Formula: 10mg per serving (optimal therapeutic dose)
Bioavailability: High oral bioavailability, absorbed in the small intestine
Timing: Best taken with food to minimize gastric irritation

Pairing Suggestions:

Synergistic with: B12, folate, magnesium, zinc
Compatible with: Other B vitamins, amino acids, minerals
Enhanced by: Riboflavin (B2) for optimal enzyme function
Best taken: With meals for optimal absorption and tolerance

Scientific References

Vitamin B6 - Health Professional Fact Sheet - NIH Office of Dietary Supplements, 2024
Vitamin B6 (Pyridoxine) - StatPearls - NCBI Bookshelf, 2023
High-Dose Vitamin B6 Displays Strong Anti-Inflammatory Properties - PMC, 2023
Vitamin B6 Deficiency - PubMed, 2017

Related Orbelli Products

Women's Hormonal Balance - Features 10mg Vitamin B6 for neurotransmitter synthesis and hormonal regulation
Synergistically combined with myo-inositol and other hormone-supporting ingredients
Additional product links to be added

Last updated: August 2025 | This information is for educational purposes only and not intended as medical advice.